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Merck
CN
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主要文件

安全信息

8.55051

Sigma-Aldrich

Biotin NovaTag® resin

Novabiochem®

别名:

N-Biotin-NÆ-Fmoc-ethylenediamine MPB-AM resin

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About This Item

UNSPSC代码:
12352209

价格与库存信息目前不能提供

产品线

NovaSyn® TG
Novabiochem®

表单

beads

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

amine

储存温度

15-25°C

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此商品
855145855054855058
functional group

amine

functional group

Fmoc, amine

functional group

amine

functional group

amine

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

product line

NovaSyn® TG, Novabiochem®

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

15-25°C

form

beads

form

beads

form

beads

form

beads

一般描述

Biotin NovaTag resin is an ideal tool for the synthesis of peptides labeled with biotin. As the biotin moiety is incorporated into the linker, its use eliminates the problems associated with biotin-labeling of peptides, namely poor solubility and sluggish coupling kinetics of biotin and its derivatives. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the peptide labeled with biotin. For a recent applications see [1,2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] M. Carraz, et al. (2009) Chemistry & Biology, 16, 702.
[2] S. Millward, et al. (2007) Chem. Biol., 2, 625.

联系

Replaces: 04-12-3901

分析说明

Color (visual): white to light yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.35 - 0.65 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer metrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

法律信息

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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    Biotin-labelled peptides find applications in immunology and histochemistry for affinity purification and receptor localization.

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