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Merck
CN
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主要文件

安全信息

8.51027

Sigma-Aldrich

Biotin-ONp

Novabiochem®

别名:

Biotin-ONp, Biotin p-nitrophenyl ester,5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid p-nitrophenyl ester

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1 G
CN¥2,076.86

CN¥2,076.86


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1 G
CN¥2,076.86

About This Item

经验公式(希尔记法):
C16H19N3O5S
CAS号:
分子量:
365.40
MDL编号:
UNSPSC代码:
12352108
NACRES:
NA.22

CN¥2,076.86


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质量水平

产品线

Novabiochem®

方案

≥97.0% (HPLC)
≥98% (TLC)

表单

powder

反应适用性

reaction type: Biotinylations

制造商/商品名称

Novabiochem®

mp

163-165 °C

应用

peptide synthesis

储存温度

15-25°C

SMILES字符串

S1[C@H]([C@H]3NC(=O)N[C@H]3C1)CCCCC(=O)Oc2ccc(cc2)[N+](=O)[O-]

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此商品
861650QBD10200203112
Biotin-ONp Novabiochem®

851027

Biotin-ONp

Biotin-NHS

203112

Biotin-NHS

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

100

reaction suitability

reaction type: Biotinylations

reaction suitability

-

reaction suitability

-

reaction suitability

-

storage temp.

15-25°C

storage temp.

-

storage temp.

−20°C

storage temp.

2-8°C

mp

163-165 °C

mp

163-165 °C (lit.)

mp

-

mp

-

form

powder

form

powder

form

solid or viscous liquid

form

solid

一般描述

Pre-activated reagent for the introduction of biotin by solid phase synthesis. More soluble and more reactive than 851023 [1]. This reagents has recently been found to be effective in SPOT synthesis of biotinylated peptides [2].

Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Literature references

[1] B. Baumeister, et al. Int. J. Pept. Res. Ther., 11, 139.
[2] D. Winkler & P. McGeer (2008) Proteomics, 8, 961.

应用

  • Mechanistic studies of a cell-permeant peptide designed to enhance myosin light chain phosphorylation: This study discusses the synthesis and applications of cell-permeant peptides involving biotin-ONP for enhanced cellular processes (Almansour, 2017).
  • Structure-function analysis of tight junction-directed permeation enhancer PIP250: Provides insights into the utility of biotin-ONP in analyzing the structure and function of peptides used to enhance cellular permeation (Taverner et al., 2023).

联系

Replaces: 01-63-0116

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in dioxan): +34.5 - +39.5 °
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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    Biotin-labelled peptides find applications in immunology and histochemistry for affinity purification and receptor localization.

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