USP20
ubiquitin specific peptidase 20
别名:
LSFR3A, VDU2, hVDU2
物种:
Human USP20 (10868), Mouse Usp20 (74270), Rat Usp20 (311856), domestic cat USP20 (101086431), dog USP20 (480696), Zebrafish usp20 (393962), chicken USP20 (417188), domestic guinea pig Usp20 (100729086), naked mole-rat Usp20 (101701963), cow USP20 (505839) ...展开
UniProtKB ID:
基因ID:
- Human(10868) Summary: This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
- Mouse(74270) ubiquitin specific peptidase 20
- Rat(311856) ubiquitin specific peptidase 20
- domestic cat(101086431) ubiquitin specific peptidase 20
- dog(480696) ubiquitin specific peptidase 20
- Zebrafish(393962) ubiquitin specific protease 20
- chicken(417188) ubiquitin specific peptidase 20
- domestic guinea pig(100729086) ubiquitin specific peptidase 20
- naked mole-rat(101701963) ubiquitin specific peptidase 20
- cow(505839) ubiquitin specific peptidase 20
- Horse(100066778) ubiquitin specific peptidase 20
- sheep(101102635) ubiquitin specific peptidase 20
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Antibodies
货号
说明
物种反应性
应用
Anti-USP20 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot