UHRF1
ubiquitin-like with PHD and ring finger domains 1
别名:
ICBP90, Np95, RNF106, hNP95, hUHRF1
物种:
Human UHRF1 (29128), Mouse Uhrf1 (18140), Rat Uhrf1 (316129), chicken UHRF1 (420154), Zebrafish uhrf1 (406350), Zebrafish uhrf1 (100538017), naked mole-rat Uhrf1 (101719703), domestic guinea pig Uhrf1 (100719542), sheep UHRF1 (101113067), cow UHRF1 (530411) ...展开
UniProtKB ID:
基因ID:
- Human(29128) Summary: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18140) ubiquitin-like, containing PHD and RING finger domains, 1
- Rat(316129) ubiquitin-like with PHD and ring finger domains 1
- chicken(420154) ubiquitin-like with PHD and ring finger domains 1
- Zebrafish(406350) ubiquitin-like, containing PHD and RING finger domains, 1
- Zebrafish(100538017) ubiquitin-like with PHD and ring finger domains 1
- naked mole-rat(101719703) ubiquitin-like with PHD and ring finger domains 1
- domestic guinea pig(100719542) ubiquitin-like with PHD and ring finger domains 1
- sheep(101113067) ubiquitin-like with PHD and ring finger domains 1
- cow(530411) ubiquitin-like with PHD and ring finger domains 1
- Horse(100062347) ubiquitin-like with PHD and ring finger domains 1
- domestic cat(101083658) ubiquitin-like with PHD and ring finger domains 1
- dog(611463) ubiquitin-like with PHD and ring finger domains 1
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Antibodies
货号
说明
物种反应性
应用
抗-ICBP90/UHRF1抗体，克隆1RC1C-10, ascites fluid, clone 1RC-1C10, from mouse,
物种反应性
human
应用
ChIP
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-E3 ubiquitin-protein ligase UHRF1 Antibody, clone 7C8, clone 7C8, 1 mg/mL, from mouse,
物种反应性
human
应用
ChIP
immunocytochemistry
western blot
immunocytochemistry
western blot
单克隆抗UHRF1 小鼠抗, clone 3A11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-UHRF1 antibody produced in mouse, clone 3B12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-E3 ubiquitin-protein ligase UHRF1, clone BF18.11 Antibody, clone BF18.11, from mouse,
物种反应性
mouse
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot