TP53
tumor protein p53
别名:
BCC7, LFS1, P53, TRP53
物种:
Human TP53 (7157), Rat Tp53 (24842), Domestic Rabbit TP53 (100009292), domestic guinea pig Tp53 (100379269), sheep TP53 (443421), cow TP53 (281542), Zebrafish tp53 (30590), naked mole-rat Tp53 (101701769), dog TP53 (403869), chicken TP53 (396200) ...展开
UniProtKB ID:
基因ID:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- sheep(443421) tumor protein p53
- cow(281542) tumor protein p53
- Zebrafish(30590) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
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ELISA
Antibodies
货号
说明
物种反应性
应用
抗-p53（野生型）抗体，克隆PAb1620, clone Pab1620, from mouse,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
western blot
抗-p53 抗体，aa 211-220，克隆240, clone PAb240, Chemicon®, from mouse,
物种反应性
bovine, chicken, hamster, human, monkey, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
物种反应性
feline, human
应用
抗-P53（Ab-5）（野生型）小鼠mAb（PAb1620）, liquid, clone PAb1620, Calbiochem®,
物种反应性
bovine, human, mouse, primate, rat
应用
Cell Lines
Small Molecule - Inhibitor
货号
说明
物种
Proteins
货号
说明
物种
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
物种
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物种
human
esiRNA
货号
说明
物种