跳转至内容
Merck
CN

TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

别名:
AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
物种:
Human TGFBR2 (7048), Mouse Tgfbr2 (21813), Rat Tgfbr2 (81810), Horse TGFBR2 (100033860), Zebrafish tgfbr2 (30739), chicken TGFBR2 (396399), domestic guinea pig Tgfbr2 (100718284), dog TGFBR2 (477039), domestic cat TGFBR2 (101091725), cow TGFBR2 (535376) ...展开
UniProtKB ID:
P37173, B4DTV5, Q15580, Q6DKT6, Q99474
基因ID:
  • Human(7048) Summary: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(21813) transforming growth factor, beta receptor II
  • Rat(81810) transforming growth factor, beta receptor II
  • Horse(100033860) transforming growth factor, beta receptor II (70/80kDa)
  • Zebrafish(30739) transforming growth factor, beta receptor II
  • chicken(396399) transforming growth factor, beta receptor II (70/80kDa)
  • domestic guinea pig(100718284) transforming growth factor, beta receptor II (70/80kDa)
  • dog(477039) transforming growth factor, beta receptor II (70/80kDa)
  • domestic cat(101091725) transforming growth factor, beta receptor II (70/80kDa)
  • cow(535376) transforming growth factor, beta receptor II (70/80kDa)
  • sheep(494191) transforming growth factor, beta receptor II (70/80kDa)
  • naked mole-rat(101704397) transforming growth factor, beta receptor II (70/80kDa)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

货号
说明
物种
RAB0553
人类TGFBR2 /TGF-β受体2型ELISA试剂盒, for serum, plasma, cell culture supernatants and urine,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4502960
Anti-TGF β Receptor II antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
SAB5700739
Anti-TGFBR2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
AV44743
Anti-TGFBR2 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human, rabbit
应用
western blot
ZRB1722
Anti-TGFBR2 Antibody, clone 1N11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
SAB4504269
Anti-phospho-TGF β Receptor II (pSer225/250) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

Proteins

货号
说明
物种
T0203
TGFβR2 (190-端)，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU020151
MISSION® esiRNA, targeting mouse Tgfbr2,
物种
mouse