TDG
thymine-DNA glycosylase
别名:
hTDG
物种:
Human TDG (6996), Mouse Tdg (21665), Rat Tdg (114521), chicken TDG (395510), Zebrafish tdg (553789), sheep TDG (101123623), cow TDG (517825), Horse TDG (100053458), domestic cat TDG (101082502), dog TDG (475448) ...展开
UniProtKB ID:
基因ID:
- Human(6996) Summary: The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
- Mouse(21665) thymine DNA glycosylase
- Rat(114521) thymine-DNA glycosylase
- chicken(395510) thymine-DNA glycosylase
- Zebrafish(553789) thymine-DNA glycosylase
- sheep(101123623) thymine-DNA glycosylase
- cow(517825) thymine-DNA glycosylase
- Horse(100053458) thymine-DNA glycosylase
- domestic cat(101082502) thymine-DNA glycosylase
- dog(475448) thymine-DNA glycosylase
- naked mole-rat(101703457) thymine-DNA glycosylase
- domestic guinea pig(100724604) thymine-DNA glycosylase
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Antibodies
货号
说明
物种反应性
应用
Anti-Thymine-DNA Glycosylase Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
immunocytochemistry
western blot
western blot
Anti-TDG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-TDG antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot