SPO11
SPO11 meiotic protein covalently bound to DSB
别名:
CT35, SPATA43, TOPVIA
物种:
Human SPO11 (23626), Mouse Spo11 (26972), Rat Spo11 (366261), domestic guinea pig Spo11 (100725083), naked mole-rat Spo11 (101706565), cow SPO11 (524105), sheep SPO11 (101118122), Domestic Rabbit SPO11 (100359270), Horse SPO11 (100050365), Zebrafish spo11 (402982) ...展开
UniProtKB ID:
基因ID:
- Human(23626) Summary: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008]
- Mouse(26972) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Rat(366261) SPO11 meiotic protein covalently bound to DSB
- domestic guinea pig(100725083) SPO11 meiotic protein covalently bound to DSB
- naked mole-rat(101706565) SPO11 meiotic protein covalently bound to DSB
- cow(524105) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- sheep(101118122) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Domestic Rabbit(100359270) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Horse(100050365) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- Zebrafish(402982) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- chicken(768915) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- dog(610247) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
- domestic cat(101090003) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
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Antibodies
货号
说明
物种反应性
应用
Anti-SPO11 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, human, rat
应用
western blot
抗-SPO11抗体，克隆180, clone 180, from mouse,
物种反应性
mouse
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-SPO11 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot