跳转至内容
Merck
CN

SOCS1

suppressor of cytokine signaling 1

别名:
CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
物种:
UniProtKB ID:
基因ID:
  • Human(8651) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
  • Mouse(12703) suppressor of cytokine signaling 1
  • Rat(252971) suppressor of cytokine signaling 1
  • naked mole-rat(101729320) suppressor of cytokine signaling 1
  • domestic guinea pig(100728652) suppressor of cytokine signaling 1
  • cow(518795) suppressor of cytokine signaling 1
  • sheep(101107324) suppressor of cytokine signaling 1
  • dog(490006) suppressor of cytokine signaling 1
  • chicken(416630) suppressor of cytokine signaling 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-SOCS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-SOCS1 Antibody, clone 4H1, clone 4H1, Upstate®, from mouse,
物种反应性
human, mouse
应用
immunoprecipitation (IP)
western blot
Anti-SOCS1 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, human, mouse, pig, rabbit, rat
应用
immunohistochemistry
western blot
Anti-SOCS1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-SOCS1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® 长非编码 esiRNA, targeting human SOCS1,
物种
human
MISSION® esiRNA, targeting mouse Socs1,
物种
mouse