跳转至内容
Merck
CN

RIN2

Ras and Rab interactor 2

别名:
MACS, RASSF4
物种:
UniProtKB ID:
基因ID:
  • Human(54453) Summary: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
  • Mouse(74030) Ras and Rab interactor 2
  • Rat(311494) Ras and Rab interactor 2
  • domestic guinea pig(100725411) Ras and Rab interactor 2
  • naked mole-rat(101723666) Ras and Rab interactor 2
  • Thale Cress(828626) E3 ubiquitin protein ligase RIN2
  • sheep(101123061) Ras and Rab interactor 2
  • cow(537459) Ras and Rab interactor 2
  • dog(477139) Ras and Rab interactor 2
  • domestic cat(101080627) Ras and Rab interactor 2
  • chicken(421246) Ras and Rab interactor 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-RIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-RIN2, (C-terminal) antibody produced in mouse, clone 1E6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human RIN2,
物种
human
MISSION® esiRNA, targeting mouse Rin2,
物种
mouse