RBPJ
recombination signal binding protein for immunoglobulin kappa J region
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
Human RBPJ (3516), Mouse Rbpj (19664), Rat Rbpj (679028), domestic guinea pig Rbpj (100716535), naked mole-rat Rbpj (101726624), dog RBPJ (479122), Horse RBPJ (100055547), cow RBPJ (767928), sheep RBPJ (101107196), domestic cat RBPJ (101100207)
- Human(3516) Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011]
- Mouse(19664) recombination signal binding protein for immunoglobulin kappa J region
- Rat(679028) recombination signal binding protein for immunoglobulin kappa J region
- domestic guinea pig(100716535) recombination signal binding protein for immunoglobulin kappa J region
- naked mole-rat(101726624) recombination signal binding protein for immunoglobulin kappa J region
- dog(479122) recombination signal binding protein for immunoglobulin kappa J region
- Horse(100055547) recombination signal binding protein for immunoglobulin kappa J region
- cow(767928) recombination signal binding protein for immunoglobulin kappa J region
- sheep(101107196) recombination signal binding protein for immunoglobulin kappa J region
- domestic cat(101100207) recombination signal binding protein for immunoglobulin kappa J region
- chicken(422802) recombination signal binding protein for immunoglobulin kappa J region
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Anti-RBPJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
human
immunofluorescence
Anti-RBPJ Antibody, clone 2D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
human, mouse, rat
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-RBP-Jk Antibody, Chemicon®, from rabbit,
human, mouse
ChIP
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-RBPJ antibody produced in rabbit, affinity isolated antibody,
bovine, dog, guinea pig, horse, human, rabbit, rat
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-RBP-Jk, clone 1F1 Antibody, clone 1F1, from rat,
drosophila, human
ChIP
electrophoretic mobility shift assay
immunoprecipitation (IP)
electrophoretic mobility shift assay
immunoprecipitation (IP)