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Merck
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RBPJ

recombination signal binding protein for immunoglobulin kappa J region

别名:
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
物种:
UniProtKB ID:
基因ID:
  • Human(3516) Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011]
  • Mouse(19664) recombination signal binding protein for immunoglobulin kappa J region
  • Rat(679028) recombination signal binding protein for immunoglobulin kappa J region
  • domestic guinea pig(100716535) recombination signal binding protein for immunoglobulin kappa J region
  • naked mole-rat(101726624) recombination signal binding protein for immunoglobulin kappa J region
  • dog(479122) recombination signal binding protein for immunoglobulin kappa J region
  • Horse(100055547) recombination signal binding protein for immunoglobulin kappa J region
  • cow(767928) recombination signal binding protein for immunoglobulin kappa J region
  • sheep(101107196) recombination signal binding protein for immunoglobulin kappa J region
  • domestic cat(101100207) recombination signal binding protein for immunoglobulin kappa J region
  • chicken(422802) recombination signal binding protein for immunoglobulin kappa J region

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Antibodies

货号
说明
物种反应性
应用
Anti-RBPJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-RBPJ Antibody, clone 2D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-RBP-Jk Antibody, Chemicon®, from rabbit,
物种反应性
human, mouse
应用
ChIP
immunohistochemistry

western blot
Anti-RBPJ antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, rabbit, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-RBP-Jk, clone 1F1 Antibody, clone 1F1, from rat,
物种反应性
drosophila, human
应用
ChIP
electrophoretic mobility shift assay

immunoprecipitation (IP)

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human RBPJ,
物种
human
MISSION® esiRNA, targeting mouse Rbpj,
物种
mouse