PTCH1
patched 1
别名:
BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11
物种:
Human PTCH1 (5727), Mouse Ptch1 (19206), Rat Ptch1 (89830), cow PTCH1 (520994), sheep PTCH1 (101112193), Domestic Rabbit PTCH1 (100345046), domestic guinea pig Ptch1 (100729719), Horse PTCH1 (100033936), Zebrafish ptch1 (30189), chicken PTCH1 (395806) ...展开
UniProtKB ID:
基因ID:
- Human(5727) Summary: This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008]
- Mouse(19206) patched homolog 1
- Rat(89830) patched 1
- cow(520994) patched 1
- sheep(101112193) patched 1
- Domestic Rabbit(100345046) patched 1
- domestic guinea pig(100729719) patched 1
- Horse(100033936) patched 1
- Zebrafish(30189) patched 1
- chicken(395806) patched 1
- dog(484137) patched 1
- domestic cat(101085077) patched 1
- naked mole-rat(101711146) patched 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-PTCH1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-PTCH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-Protein patched homolog 1 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
western blot
Anti-PATCHED, N-Terminal antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PTCH antibody produced in mouse, clone 8E1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot