PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
别名:
TBP1
物种:
Human PSMC3 (5702), Mouse Psmc3 (19182), Rat Psmc3 (29677), Zebrafish psmc3 (321947), chicken PSMC3 (423182), domestic guinea pig Psmc3 (100727371), naked mole-rat Psmc3 (101706267), sheep PSMC3 (101117873), Domestic Rabbit PSMC3 (100354000), cow PSMC3 (508448) ...展开
UniProtKB ID:
基因ID:
- Human(5702) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008]
- Mouse(19182) proteasome (prosome, macropain) 26S subunit, ATPase 3
- Rat(29677) proteasome (prosome, macropain) 26S subunit, ATPase 3
- Zebrafish(321947) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- chicken(423182) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- domestic guinea pig(100727371) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- naked mole-rat(101706267) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- sheep(101117873) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- Domestic Rabbit(100354000) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- cow(508448) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- Horse(100051468) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- domestic cat(101095435) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- dog(475980) proteasome (prosome, macropain) 26S subunit, ATPase, 3
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Antibodies
货号
说明
物种反应性
应用
Anti-PSMC3 (ab1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast
应用
western blot
Anti-PSMC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PSMC3 antibody produced in mouse, clone 1B9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-PRS6A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-PSMC3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, rat
应用
western blot