PRKCI
protein kinase C, iota
别名:
DXS1179E, PKCI, nPKC-iota
物种:
Human PRKCI (5584), Mouse Prkci (18759), Rat Prkci (84006), domestic guinea pig Prkci (100731983), naked mole-rat Prkci (101697279), sheep PRKCI (101118322), Horse PRKCI (100063737), cow PRKCI (528478), dog PRKCI (478686), domestic cat PRKCI (101087000) ...展开
UniProtKB ID:
基因ID:
- Human(5584) Summary: This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
- Mouse(18759) protein kinase C, iota
- Rat(84006) protein kinase C, iota
- domestic guinea pig(100731983) protein kinase C, iota
- naked mole-rat(101697279) protein kinase C, iota
- sheep(101118322) protein kinase C, iota
- Horse(100063737) protein kinase C, iota
- cow(528478) protein kinase C, iota
- dog(478686) protein kinase C, iota
- domestic cat(101087000) protein kinase C, iota
- chicken(424991) protein kinase C, iota
- Zebrafish(117507) protein kinase C, iota
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-PRKCI antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PRKCI, (N-terminal) antibody produced in mouse, clone 3A7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
ANTI-PKC IOTA(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-PRKCI antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Monoclonal Anti-PRKCI antibody produced in mouse, clone 1G11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种
PKC iota Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6-tagged, recombinant full-length human PKC iota. For use in Kinase Assays.,
物种
human
PKCι，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human