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Merck
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PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

别名:
AMPK, AMPKa1
物种:
Human PRKAA1 (5562), Mouse Prkaa1 (105787), Rat Prkaa1 (65248), Horse PRKAA1 (100009710), sheep PRKAA1 (100294665), dog PRKAA1 (479351), domestic guinea pig Prkaa1 (100714483), Zebrafish prkaa1 (100001198), chicken PRKAA1 (427185), cow PRKAA1 (540404) ...展开
UniProtKB ID:
Q13131, A8MTQ6, B2R7E1, O00286, Q5D0E1, Q86VS1, Q9UNQ4
基因ID:
  • Human(5562) Summary: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(105787) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Rat(65248) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Horse(100009710) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • sheep(100294665) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • dog(479351) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • domestic guinea pig(100714483) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Zebrafish(100001198) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • chicken(427185) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • cow(540404) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • naked mole-rat(101722998) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • sheep(101103425) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • domestic cat(101095885) protein kinase, AMP-activated, alpha 1 catalytic subunit

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Antibodies

货号
说明
物种反应性
应用
07-681
抗磷酸化AMPK α(Thr172) 抗体, Upstate®, from rabbit,
物种反应性
human, rat
应用
western blot
ZRB1100
Anti-AMPK alpha Antibody, clone 2D22, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry
western blot
SAB5600112
Anti-AMPK alpha-1antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM301, purified immunoglobulin,
物种反应性
human
应用
immunohistochemistry
western blot
HPA035409
Anti-PRKAA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
SAB5700715
Anti-AMPK alpha 1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot

Proteins

货号
说明
物种
A1233
AMPK (α1/β1/γ1)，活性，His标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
A4486
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
A4611
AMPK (α1/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU190491
MISSION® esiRNA, targeting mouse Prkaa1,
物种
mouse
EHU074041
MISSION® esiRNA, targeting human PRKAA1,
物种
human