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PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

别名:
AMPK, AMPKa1
物种:
UniProtKB ID:
基因ID:
  • Human(5562) Summary: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(105787) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Rat(65248) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Horse(100009710) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • sheep(100294665) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • dog(479351) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • domestic guinea pig(100714483) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Zebrafish(100001198) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • chicken(427185) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • cow(540404) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • naked mole-rat(101722998) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • sheep(101103425) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • domestic cat(101095885) protein kinase, AMP-activated, alpha 1 catalytic subunit

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Antibodies

货号
说明
物种反应性
应用
抗磷酸化AMPK α(Thr172) 抗体, Upstate®, from rabbit,
物种反应性
human, rat
应用
western blot
Anti-AMPK alpha Antibody, clone 2D22, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-AMPK alpha 1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
Anti-AMPK alpha-1antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM301, purified immunoglobulin,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-phospho-AMPK alpha-1 Antibody, (Thr479), from rabbit, purified by affinity chromatography,
物种反应性
bovine, horse, human, mouse, porcine, rat
应用
dot blot
western blot

Proteins

货号
说明
物种
AMPK (α1/β1/γ1),活性,His标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
AMPK (α1/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PRKAA1,
物种
human
MISSION® esiRNA, targeting mouse Prkaa1,
物种
mouse