POLG
polymerase (DNA directed), gamma
别名:
MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE
物种:
Human POLG (5428), Mouse Polg (18975), Rat Polg (85472), Zebrafish polg (100150924), Horse POLG (100053827), dog POLG (488732), naked mole-rat Polg (101700433), domestic cat POLG (101083771), cow POLG (533090), chicken POLG (404292) ...展开
UniProtKB ID:
基因ID:
- Human(5428) Summary: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18975) polymerase (DNA directed), gamma
- Rat(85472) polymerase (DNA directed), gamma
- Zebrafish(100150924) polymerase (DNA directed), gamma
- Horse(100053827) polymerase (DNA directed), gamma
- dog(488732) polymerase (DNA directed), gamma
- naked mole-rat(101700433) polymerase (DNA directed), gamma
- domestic cat(101083771) polymerase (DNA directed), gamma
- cow(533090) polymerase (DNA directed), gamma
- chicken(404292) polymerase (DNA directed), gamma
- sheep(101123414) polymerase (DNA directed), gamma
- domestic guinea pig(100728907) polymerase (DNA directed), gamma
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Antibodies
货号
说明
物种反应性
应用
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
抗-DNA聚合酶亚基γ-1抗体/POLG, 1.0 mg/mL, from rabbit,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)
immunoprecipitation (IP)
Anti-DNA Polymerase gamma Antibody, clone 9V9D9, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot
Small Molecule - Inhibitor
货号
说明
物种