A0781
Aphidicolin from Nigrospora sphaerica
≥98% (HPLC), DNA polymerase inhibitor, powder
别名:
APC
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关于此项目
经验公式（希尔记法）:
C20H34O4
化学文摘社编号:
分子量:
338.48
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
4689958
Assay:
≥98% (HPLC)
Form:
powder
产品名称
Aphidicolin from Nigrospora sphaerica, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]27/D +12°, c = 1 in methanol(lit.)
color
white
mp
227-233 °C (lit.)
solubility
ethanol: 1 mg/mL (stable at least a week at 4°C.), DMSO: 10 mg/mL (stable at least six weeks at −20°C.), methanol: 10 mg/mL, H2O: insoluble
antibiotic activity spectrum
neoplastics, viruses
mode of action
DNA synthesis | interferes
storage temp.
2-8°C
SMILES string
[H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4
InChI
1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
InChI key
NOFOAYPPHIUXJR-APNQCZIXSA-N
Gene Information
human ... POLA1(5422), POLD1(5424), POLG(5428)
Biochem/physiol Actions
Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
Features and Benefits
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Disclaimer
Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)