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Merck
CN

PDE1A

phosphodiesterase 1A, calmodulin-dependent

别名:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
物种:
Human PDE1A (5136), Mouse Pde1a (18573), Rat Pde1a (81529), chicken PDE1A (424116), Zebrafish pde1a (564465), domestic cat PDE1A (101083101), dog PDE1A (403652), naked mole-rat Pde1a (101712147), sheep PDE1A (101119369), Domestic Rabbit PDE1A (100346878) ...展开
UniProtKB ID:
P54750, D3DPG5, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2
基因ID:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

货号
说明
物种反应性
应用
HPA022151
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
SAB1409417
Anti-PDE1A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
SAB1410919
Anti-PDE1A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
M2547
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
物种
human
1220506
双嘧达莫, United States Pharmacopeia (USP) Reference Standard,
物种
human
BP1102
双嘧达莫杂质标准品, British Pharmacopoeia (BP) Reference Standard,
物种
human
Y0000802
双嘧达莫, European Pharmacopoeia (EP) Reference Standard,
物种
human
D2850000
双嘧达莫, European Pharmacopoeia (EP) Reference Standard,
物种
human

Proteins

货号
说明
物种
SRP0257
PDE1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
EHU074801
MISSION® esiRNA, targeting human PDE1A,
物种
human
EMU077501
MISSION® esiRNA, targeting mouse Pde1a,
物种
mouse