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Merck
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PDE1A

phosphodiesterase 1A, calmodulin-dependent

Synonyms:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Species:
Human PDE1A (5136), Mouse Pde1a (18573), Rat Pde1a (81529), chicken PDE1A (424116), Zebrafish pde1a (564465), domestic cat PDE1A (101083101), dog PDE1A (403652), naked mole-rat Pde1a (101712147), sheep PDE1A (101119369), Domestic Rabbit PDE1A (100346878) ...More
UniProtKB ID:
P54750, D3DPG5, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2
Gene ID:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA022151
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
M2547
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Species
human
1220506
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Species
human
D2850000
Dipyridamole, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP1102
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Species
human
BP131
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
EMU077501
MISSION® esiRNA, targeting mouse Pde1a,
Species
mouse
EHU074801
MISSION® esiRNA, targeting human PDE1A,
Species
human