PATZ1
POZ (BTB) and AT hook containing zinc finger 1
别名:
MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG, dJ400N23
物种:
Human PATZ1 (23598), Mouse Patz1 (56218), Rat Patz1 (305471), dog PATZ1 (486365), Horse PATZ1 (100058375), Zebrafish patz1 (560290), Domestic Rabbit PATZ1 (100328729), naked mole-rat Patz1 (101699786), domestic cat PATZ1 (101097426), domestic guinea pig Patz1 (100730234) ...展开
UniProtKB ID:
基因ID:
- Human(23598) Summary: The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(56218) POZ (BTB) and AT hook containing zinc finger 1
- Rat(305471) POZ (BTB) and AT hook containing zinc finger 1
- dog(486365) POZ (BTB) and AT hook containing zinc finger 1
- Horse(100058375) POZ (BTB) and AT hook containing zinc finger 1
- Zebrafish(560290) POZ (BTB) and AT hook containing zinc finger 1
- Domestic Rabbit(100328729) POZ (BTB) and AT hook containing zinc finger 1
- naked mole-rat(101699786) POZ (BTB) and AT hook containing zinc finger 1
- domestic cat(101097426) POZ (BTB) and AT hook containing zinc finger 1
- domestic guinea pig(100730234) POZ (BTB) and AT hook containing zinc finger 1
- cow(532416) POZ (BTB) and AT hook containing zinc finger 1
- sheep(101115906) POZ (BTB) and AT hook containing zinc finger 1
- chicken(416963) POZ (BTB) and AT hook containing zinc finger 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-PATZ1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Anti-PATZ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry