PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
LIS1, LIS2, MDCR, MDS, PAFAH
Human PAFAH1B1 (5048), Mouse Pafah1b1 (18472), Rat Pafah1b1 (83572), naked mole-rat Pafah1b1 (101709906), chicken PAFAH1B1 (374224), dog PAFAH1B1 (480656), domestic cat PAFAH1B1 (100135766), Horse PAFAH1B1 (100072490), cow PAFAH1B1 (282513), sheep PAFAH1B1 (101119146)
- Human(5048) Summary: This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]
- Mouse(18472) platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
- Rat(83572) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
- naked mole-rat(101709906) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- chicken(374224) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- dog(480656) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- domestic cat(100135766) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- Horse(100072490) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- cow(282513) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- sheep(101119146) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- domestic guinea pig(100734716) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
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Antibodies
Anti-PAFAH1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-PAFAH1B1 antibody produced in mouse, clone 2C12, purified immunoglobulin, buffered aqueous solution,
human
ELISA
western blot
western blot
Anti-LIS1/PAFAH1B1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
canine, human, mouse, rat
ELISA
western blot
western blot
Anti-LIS1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
human, mouse, rat
ELISA
immunocytochemistry
immunofluorescence
western blot
immunocytochemistry
immunofluorescence
western blot
Monoclonal Anti-PAFAH1B1, (N-terminal) antibody produced in mouse, clone 5A5, purified immunoglobulin, buffered aqueous solution,
human
ELISA
immunofluorescence
western blot
immunofluorescence
western blot