PADI2
peptidyl arginine deiminase, type II
别名:
PAD-H19, PAD2, PDI2
物种:
Human PADI2 (11240), Mouse Padi2 (18600), Rat Padi2 (29511), dog PADI2 (487414), chicken PADI2 (428172), Zebrafish padi2 (386792), naked mole-rat Padi2 (101721485), domestic cat PADI2 (101085301), Horse PADI2 (100050025), sheep PADI2 (101108464) ...展开
UniProtKB ID:
基因ID:
- Human(11240) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
- Mouse(18600) peptidyl arginine deiminase, type II
- Rat(29511) peptidyl arginine deiminase, type II
- dog(487414) peptidyl arginine deiminase, type II
- chicken(428172) peptidyl arginine deiminase, type II
- Zebrafish(386792) peptidyl arginine deiminase, type II
- naked mole-rat(101721485) peptidyl arginine deiminase, type II
- domestic cat(101085301) peptidyl arginine deiminase, type II
- Horse(100050025) peptidyl arginine deiminase, type II
- sheep(101108464) peptidyl arginine deiminase, type II
- domestic guinea pig(100728531) peptidyl arginine deiminase, type II
- cow(617851) peptidyl arginine deiminase, type II
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-PADI2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-PADI2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, horse, human
应用
western blot
Proteins
货号
说明
物种
PAD2, GST tagged from mouse, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
mouse