MAP3K7
mitogen-activated protein kinase kinase kinase 7
别名:
MEKK7, TAK1, TGF1a
物种:
Human MAP3K7 (6885), Mouse Map3k7 (26409), Rat Map3k7 (313121), Zebrafish map3k7 (553788), Horse MAP3K7 (100065841), Domestic Rabbit MAP3K7 (100343571), dog MAP3K7 (474996), chicken MAP3K7 (421808), domestic guinea pig Map3k7 (100718100), naked mole-rat Map3k7 (101718269) ...展开
UniProtKB ID:
基因ID:
- Human(6885) Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(26409) mitogen-activated protein kinase kinase kinase 7
- Rat(313121) mitogen activated protein kinase kinase kinase 7
- Zebrafish(553788) mitogen activated protein kinase kinase kinase 7
- Horse(100065841) mitogen-activated protein kinase kinase kinase 7
- Domestic Rabbit(100343571) mitogen-activated protein kinase kinase kinase 7
- dog(474996) mitogen-activated protein kinase kinase kinase 7
- chicken(421808) mitogen-activated protein kinase kinase kinase 7
- domestic guinea pig(100718100) mitogen-activated protein kinase kinase kinase 7
- naked mole-rat(101718269) mitogen-activated protein kinase kinase kinase 7
- domestic cat(101095899) mitogen-activated protein kinase kinase kinase 7
- cow(529146) mitogen-activated protein kinase kinase kinase 7
- sheep(100294587) mitogen-activated protein kinase kinase kinase 7
- sheep(101108056) mitogen-activated protein kinase kinase kinase 7
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Antibodies
货号
说明
物种反应性
应用
Anti-phospho-TAK1 (pThr184) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-TAK1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-phospho-TAK1 (Ser412) Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
western blot
Anti-MAP3K7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Proteins
货号
说明
物种
TAK1-TAB1 fusion Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human TAK1 amino acids 1-303, fused to human TAB1 amino acids 437-end, for use in Kinase Assays.,
物种
human
TAK1-TAB1 (1-303), (437-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human