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LATS2

large tumor suppressor kinase 2

别名:
KPM
物种:
UniProtKB ID:
基因ID:
  • Human(26524) Summary: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
  • Mouse(50523) large tumor suppressor 2
  • Rat(305922) large tumor suppressor 2
  • sheep(101117941) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • naked mole-rat(101705060) large tumor suppressor kinase 2
  • Zebrafish(567674) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • Domestic Rabbit(100356876) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • domestic guinea pig(100725954) large tumor suppressor kinase 2
  • chicken(418949) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • dog(477343) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • Horse(100050150) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • domestic cat(101093824) LATS, large tumor suppressor, homolog 2 (Drosophila)
  • cow(508208) large tumor suppressor kinase 2

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Antibodies

货号
说明
物种反应性
应用
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-LATS2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunofluorescence

immunohistochemistry
Anti-phospho-LATS1/2 (pThr1079/1041) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
Anti-phospho-LATS1-T1079/LATS2-T1041 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
western blot

Proteins

货号
说明
物种
LATS2 (480-1088), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human LATS2,
物种
human