KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
别名:
KCa2.3, SK3, SKCA3, hSK3
物种:
Human KCNN3 (3782), Mouse Kcnn3 (140493), Rat Kcnn3 (54263), dog KCNN3 (490441), sheep KCNN3 (101112614), naked mole-rat Kcnn3 (101721013), cow KCNN3 (534180), domestic guinea pig Kcnn3 (100733252), domestic cat KCNN3 (101097043), Zebrafish kcnn3 (570138)
UniProtKB ID:
基因ID:
- Human(3782) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
- Mouse(140493) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- Rat(54263) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- dog(490441) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- sheep(101112614) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- naked mole-rat(101721013) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- cow(534180) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- domestic guinea pig(100733252) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- domestic cat(101097043) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
- Zebrafish(570138) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
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Antibodies
货号
说明
物种反应性
应用
Anti-KCNN3 (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Anti-KCNN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-Potassium Channel SK3 (KCa3, Kcnn3, SKCa3) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
human, rat
应用
western blot
Anti-Potassium Channel KCa2.3, (C-term) (Small-conductance Ca2+-activated Potassium Channel 3) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
human, mouse, pig, rat
应用
western blot