HLA-F
major histocompatibility complex, class I, F
别名:
CDA12, HLA-5.4, HLA-CDA12, HLAF
物种:
UniProtKB ID:
基因ID:
- Human(3134) Summary: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
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Antibodies
货号
说明
物种反应性
应用
Anti-HLA-F antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, pig
应用
immunohistochemistry
western blot
western blot
esiRNA
货号
说明
物种