GTF2A2
general transcription factor IIA, 2, 12kDa
Synonyms:
HsT18745, TF2A2, TFIIA
Species:
Human GTF2A2 (2958), Mouse Gtf2a2 (235459), Rat Gtf2a2 (83828), sheep GTF2A2 (101114960), dog GTF2A2 (478327), chicken GTF2A2 (770910), domestic guinea pig Gtf2a2 (100716605), Zebrafish gtf2a2 (798997), cow GTF2A2 (613479), domestic cat GTF2A2 (101100892)
UniProtKB ID:
Gene ID:
- Human(2958) Summary: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]
- Mouse(235459) general transcription factor II A, 2
- Rat(83828) general transcription factor IIA, 2
- sheep(101114960) general transcription factor IIA, 2, 12kDa
- dog(478327) general transcription factor IIA, 2, 12kDa
- chicken(770910) general transcription factor IIA, 2, 12kDa
- domestic guinea pig(100716605) general transcription factor IIA, 2, 12kDa
- Zebrafish(798997) general transcription factor IIA, 2
- cow(613479) general transcription factor IIA, 2, 12kDa
- domestic cat(101100892) general transcription factor IIA, 2, 12kDa
- naked mole-rat(101725193) general transcription factor IIA, 2, 12kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GTF2A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
ChIP
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-GTF2A2 antibody produced in mouse, clone 2B9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species