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Merck
CN

GPBAR1

G protein-coupled bile acid receptor 1

别名:
BG37, GPCR19, GPR131, M-BAR, TGR5
物种:
UniProtKB ID:
基因ID:
  • Human(151306) Summary: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(227289) G protein-coupled bile acid receptor 1
  • Rat(338443) G protein-coupled bile acid receptor 1
  • naked mole-rat(101710900) G protein-coupled bile acid receptor 1
  • domestic guinea pig(100723590) G protein-coupled bile acid receptor 1
  • sheep(101109073) G protein-coupled bile acid receptor 1
  • cow(317756) G protein-coupled bile acid receptor 1
  • domestic cat(101089457) G protein-coupled bile acid receptor 1
  • dog(488521) G protein-coupled bile acid receptor 1

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Antibodies

货号
说明
物种反应性
应用
Anti-GPBAR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Gpbar1,
物种
mouse
MISSION® esiRNA, targeting human GPBAR1,
物种
human