跳转至内容
Merck
CN

GP1BA

glycoprotein Ib (platelet), alpha polypeptide

别名:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
物种:
UniProtKB ID:
基因ID:
  • Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
  • Mouse(14723) glycoprotein 1b, alpha polypeptide
  • Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
  • chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
  • naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
  • domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
  • sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
  • cow(504977) glycoprotein Ib (platelet), alpha polypeptide
  • domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
  • dog(403638) glycoprotein Ib (platelet), alpha polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

货号
说明
物种
人CD42b ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-CD42B antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP219, affinity isolated antibody,
物种反应性
dog, human, mouse
应用
flow cytometry
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, nonhuman primates
应用
flow cytometry
Anti-GP1BA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone AK2,
物种反应性
human
应用
flow cytometry
Monoclonal Anti-GP1BA antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Gp1ba,
物种
mouse
MISSION® esiRNA, targeting human GP1BA,
物种
human