ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2
别名:
COFS2, EM9, TTD, XPD
物种:
Human ERCC2 (2068), Mouse Ercc2 (13871), Rat Ercc2 (308415), domestic guinea pig Ercc2 (100721308), domestic cat ERCC2 (101095702), Domestic Rabbit ERCC2 (100347957), sheep ERCC2 (101116341), naked mole-rat Ercc2 (101697378), Zebrafish ercc2 (393900), cow ERCC2 (100125238)
UniProtKB ID:
基因ID:
- Human(2068) Summary: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(13871) excision repair cross-complementing rodent repair deficiency, complementation group 2
- Rat(308415) excision repair cross-complementing rodent repair deficiency, complementation group 2
- domestic guinea pig(100721308) excision repair cross-complementing rodent repair deficiency, complementation group 2
- domestic cat(101095702) excision repair cross-complementing rodent repair deficiency, complementation group 2
- Domestic Rabbit(100347957) excision repair cross-complementing rodent repair deficiency, complementation group 2
- sheep(101116341) excision repair cross-complementing rodent repair deficiency, complementation group 2
- naked mole-rat(101697378) excision repair cross-complementing rodent repair deficiency, complementation group 2
- Zebrafish(393900) excision repair cross-complementing rodent repair deficiency, complementation group 2
- cow(100125238) excision repair cross-complementing rodent repair deficiency, complementation group 2
- dog(493995) excision repair cross-complementing rodent repair deficiency, complementation group 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-ERCC2 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
immunofluorescence
Anti-ERCC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-ERCC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-XPD Antibody, clone 22TF2-2F6, clone 22TF2-2F6, from mouse,
物种反应性
human
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
货号
说明
物种