EGLN1
egl-9 family hypoxia-inducible factor 1
别名:
C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6
物种:
Human EGLN1 (54583), Mouse Egln1 (112405), Rat Egln1 (308913), cow EGLN1 (534075), sheep EGLN1 (101114163), domestic guinea pig Egln1 (100726309), naked mole-rat Egln1 (101709882), Zebrafish egln1 (436868), domestic cat EGLN1 (101089964), dog EGLN1 (488971)
UniProtKB ID:
基因ID:
- Human(54583) Summary: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009]
- Mouse(112405) EGL nine homolog 1 (C. elegans)
- Rat(308913) EGL nine homolog 1 (C. elegans)
- cow(534075) egl nine homolog 1 (C. elegans)
- sheep(101114163) egl nine homolog 1 (C. elegans)
- domestic guinea pig(100726309) egl nine homolog 1 (C. elegans)
- naked mole-rat(101709882) egl nine homolog 1 (C. elegans)
- Zebrafish(436868) egl nine homolog 1 (C. elegans)
- domestic cat(101089964) egl nine homolog 1 (C. elegans)
- dog(488971) egl nine homolog 1 (C. elegans)
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Antibodies
货号
说明
物种反应性
应用
Anti-EGLN1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PHD2/EGLN1 Antibody, clone 1B12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-EGLN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-phospho-PHD2 (Ser 125) Antibody, clone 4, clone 4, from mouse,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
esiRNA
货号
说明
物种