DIABLO
diablo, IAP-binding mitochondrial protein
别名:
DFNA64, SMAC
物种:
Human DIABLO (56616), Mouse Diablo (66593), Rat Diablo (288753), chicken DIABLO (416860), cow DIABLO (493999), domestic guinea pig Diablo (100724526), naked mole-rat Diablo (101708166), sheep DIABLO (101121971), dog DIABLO (477463)
UniProtKB ID:
基因ID:
- Human(56616) Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Mouse(66593) diablo homolog (Drosophila)
- Rat(288753) diablo, IAP-binding mitochondrial protein
- chicken(416860) diablo, IAP-binding mitochondrial protein
- cow(493999) diablo, IAP-binding mitochondrial protein
- domestic guinea pig(100724526) diablo, IAP-binding mitochondrial protein
- naked mole-rat(101708166) diablo, IAP-binding mitochondrial protein
- sheep(101121971) diablo, IAP-binding mitochondrial protein
- dog(477463) diablo, IAP-binding mitochondrial protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
货号
说明
物种反应性
应用
Anti-SMAC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-DIABLO antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Monoclonal Anti-DIABLO antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-DIABLO antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry