跳转至内容
Merck
CN

DAXX

death-domain associated protein

别名:
BING2, DAP6, EAP1
物种:
UniProtKB ID:
基因ID:
  • Human(1616) Summary: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
  • Mouse(13163) Fas death domain-associated protein
  • Rat(140926) death-domain associated protein
  • Zebrafish(561006) death-associated protein 6
  • domestic cat(101089265) death-domain associated protein
  • dog(474873) death-domain associated protein
  • domestic guinea pig(100730008) death-domain associated protein
  • cow(504336) death-domain associated protein
  • naked mole-rat(101717412) death-domain associated protein
  • sheep(100505403) death-domain associated protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
抗-DAXX 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-Daxx antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunocytochemistry

western blot
Monoclonal Anti-DAXX antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3580, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® 长非编码 esiRNA, targeting human DAXX,
物种
MISSION® esiRNA, targeting mouse Daxx,
物种
mouse