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Merck
CN

CKMT1B

creatine kinase, mitochondrial 1B

别名:
CKMT, CKMT1, UMTCK
物种:
UniProtKB ID:
基因ID:
  • Human(1159) Summary: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
  • Rat(29593) creatine kinase, mitochondrial 1B
  • dog(478277) creatine kinase, mitochondrial 1B
  • domestic cat(101097983) creatine kinase, mitochondrial 1B
  • Horse(100056283) creatine kinase, mitochondrial 1B
  • naked mole-rat(101725224) creatine kinase, mitochondrial 1B
  • sheep(101108520) creatine kinase, mitochondrial 1B
  • cow(281692) creatine kinase, mitochondrial 1B

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-CKMT1B, (C-terminal) antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Monoclonal Anti-CKMT1B antibody produced in mouse, clone 2C8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot