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Merck
CN

CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

别名:
BIII, CACNL1A5, CACNN, Cav2.2
物种:
Human CACNA1B (774), Mouse Cacna1b (12287), Rat Cacna1b (257648), cow CACNA1B (282410), chicken CACNA1B (374169), dog CACNA1B (480660), Domestic Rabbit CACNA1B (100008979), naked mole-rat Cacna1b (101697609), domestic guinea pig Cacna1b (100735203), domestic cat CACNA1B (101087362)
UniProtKB ID:
Q00975, B1AQK5
基因ID:
  • Human(774) Summary: The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(12287) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Rat(257648) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • cow(282410) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • chicken(374169) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • dog(480660) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Domestic Rabbit(100008979) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • naked mole-rat(101697609) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic guinea pig(100735203) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic cat(101087362) calcium channel, voltage-dependent, N type, alpha 1B subunit

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Small Molecule - Allosteric Modulator

货号
说明
物种
PHR1447
左乙拉西坦, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1359404
左乙拉西坦, United States Pharmacopeia (USP) Reference Standard,
物种
human
L-020
Levetiracetam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Y0001253
左乙拉西坦, European Pharmacopoeia (EP) Reference Standard,
物种
human
1287303
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
AB5154
抗-Cav2.2抗体, Chemicon®, from rabbit,
物种反应性
rat
应用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA044347
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
HPA022919
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
C1478
Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Blocker

货号
说明
物种
PHR1447
左乙拉西坦, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1359404
左乙拉西坦, United States Pharmacopeia (USP) Reference Standard,
物种
human
L-020
Levetiracetam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Y0001253
左乙拉西坦, European Pharmacopoeia (EP) Reference Standard,
物种
human
C9915
ω-Conotoxin GVIA, ≥97% (HPLC),
物种
mouse, rat, human

esiRNA

货号
说明
物种
EMU085171
MISSION® esiRNA, targeting mouse Cacna1b,
物种
mouse
EHU159041
MISSION® esiRNA, targeting human CACNA1B,
物种
human