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Merck
CN

APEX1

APEX nuclease (multifunctional DNA repair enzyme) 1

别名:
APE, APE1, APEN, APEX, APX, HAP1, REF1
物种:
UniProtKB ID:
基因ID:
  • Human(328) Summary: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(11792) apurinic/apyrimidinic endonuclease 1
  • Rat(79116) APEX nuclease (multifunctional DNA repair enzyme) 1
  • cow(281630) APEX nuclease (multifunctional DNA repair enzyme) 1
  • Goat(100860967) APEX nuclease (multifunctional DNA repair enzyme) 1
  • chicken(100431102) APEX nuclease (multifunctional DNA repair enzyme) 1
  • dog(482558) APEX nuclease (multifunctional DNA repair enzyme) 1
  • domestic cat(101101318) APEX nuclease (multifunctional DNA repair enzyme) 1
  • Zebrafish(406730) APEX nuclease (multifunctional DNA repair enzyme) 1
  • domestic guinea pig(100719062) APEX nuclease (multifunctional DNA repair enzyme) 1
  • naked mole-rat(101709711) APEX nuclease (multifunctional DNA repair enzyme) 1
  • sheep(101115462) APEX nuclease (multifunctional DNA repair enzyme) 1

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Antibodies

货号
说明
物种反应性
应用
Anti-APEX1 antibody produced in rabbit, ,
物种反应性
human
应用
immunofluorescence
immunoprecipitation (IP)

western blot
抗-APEX1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-APEX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-APEX1/APE1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Monoclonal Anti-APEX1 antibody produced in mouse, clone 3E12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human APEX1,
物种
human
MISSION® esiRNA, targeting mouse Apex1,
物种
mouse