AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
别名:
AIF, CMTX4, COWCK, COXPD6, PDCD8
物种:
Human AIFM1 (9131), Mouse Aifm1 (26926), Rat Aifm1 (83533), Horse AIFM1 (100054546), cow AIFM1 (535714), sheep AIFM1 (100188912), sheep AIFM1 (101121574), Zebrafish aifm1 (373125), chicken AIFM1 (428688), domestic cat AIFM1 (768258) ...展开
UniProtKB ID:
基因ID:
- Human(9131) Summary: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010]
- Mouse(26926) apoptosis-inducing factor, mitochondrion-associated 1
- Rat(83533) apoptosis-inducing factor, mitochondrion-associated 1
- Horse(100054546) apoptosis-inducing factor, mitochondrion-associated, 1
- cow(535714) apoptosis-inducing factor, mitochondrion-associated, 1
- sheep(100188912) apoptosis-inducing factor, mitochondrion-associated, 1
- sheep(101121574) apoptosis-inducing factor, mitochondrion-associated, 1
- Zebrafish(373125) apoptosis-inducing factor, mitochondrion-associated 1
- chicken(428688) apoptosis-inducing factor, mitochondrion-associated, 1
- domestic cat(768258) apoptosis-inducing factor, mitochondrion-associated, 1
- domestic guinea pig(100730787) apoptosis-inducing factor, mitochondrion-associated, 1
- naked mole-rat(101698690) apoptosis-inducing factor, mitochondrion-associated, 1
- Domestic Rabbit(100347778) apoptosis-inducing factor, mitochondrion-associated, 1
- dog(481048) apoptosis-inducing factor, mitochondrion-associated, 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-AIF Antibody, internal domain, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-AIF Antibody, clone 1E4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, feline, human, monkey, mouse, porcine, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-AIF antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot