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Merck
CN

ACTN1

actinin, alpha 1

别名:
BDPLT15
物种:
UniProtKB ID:
基因ID:
  • Human(87) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(109711) actinin, alpha 1
  • Rat(81634) actinin, alpha 1
  • Domestic Rabbit(100341378) actinin, alpha 1
  • Zebrafish(560400) actinin, alpha 1
  • naked mole-rat(101711839) actinin, alpha 1
  • domestic guinea pig(100721342) actinin, alpha 1
  • cow(524770) actinin, alpha 1
  • chicken(373918) actinin, alpha 1
  • domestic cat(101097986) actinin, alpha 1
  • dog(480369) actinin, alpha 1
  • sheep(101122194) actinin, alpha 1

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Antibodies

货号
说明
物种反应性
应用
抗-α-Actinin抗体,克隆AT6/172, clone AT6/172, Upstate®, from mouse,
物种反应性
human, mouse, rabbit
应用
immunocytochemistry
western blot
Anti-α Actinin antibody, Mouse monoclonal, clone BM-75.2, purified from hybridoma cell culture,
物种反应性
human
应用
immunofluorescence
western blot
Anti-ACTN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-α-Actinin-1 Antibody, clone 2C17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-α Actinin Antibody, clone AT6/172 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot

Proteins

货号
说明
物种
LentiBrite α-actinin-GFP Lentiviral Biosensor, ,
物种
human
LentiBrite α-actinin-RFP Lentiviral Biosensor, ,
物种
human
α-Actinin from chicken gizzard, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
物种
mouse, chicken, rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ACTN1,
物种
human
MISSION® esiRNA, targeting mouse Actn1,
物种
mouse