特异性
识别α-辅肌动蛋白。
免疫原
人α-辅肌动蛋白
应用
不建议免疫沉淀
研究子类别
细胞骨架
细胞骨架
研究类别
细胞结构
细胞结构
该抗-α-辅肌动蛋白抗体，克隆AT6/172，已经过验证可用于IC和WB中对α-辅肌动蛋白进行检测。
质量
在人A431细胞中的免疫印迹中进行了常规评估
目标描述
100 kDa
外形
形式：纯化
批次特定配方请参见产品数据表。
蛋白A纯化
储存及稳定性
自运送之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
分析说明
对照
阳性抗原对照：货号12-301，未刺激的A431细胞裂解液。加入2.5µL 2-巯基乙醇/100µL裂解液，煮沸5分钟以减少制备量。在微凝胶每个泳道上样20µg经还原的裂解液。
阳性抗原对照：货号12-301，未刺激的A431细胞裂解液。加入2.5µL 2-巯基乙醇/100µL裂解液，煮沸5分钟以减少制备量。在微凝胶每个泳道上样20µg经还原的裂解液。
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Jing Zong et al.
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Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function
Fukami, K, et al
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Never in mitosis gene A related kinase-6 attenuates pressure overload-induced activation of the protein kinase B pathway and cardiac hypertrophy.
Bian, Z; Liao, H; Zhang, Y; Wu, Q; Zhou, H; Yang, Z; Fu, J; Wang, T; Yan, L; Shen, D; Li, H; Tang, Q
Testing null
Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated beta-catenin.
Renou, JP; Bierie, B; Miyoshi, K; Cui, Y; Djiane, J; Reichenstein, M; Shani, M; Hennighausen, L
Oncogene null
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Journal of the American Heart Association, 7(13) (2018-06-28)
Carboxyl-terminal modulator protein (CTMP) has been implicated in cancer, brain injury, and obesity. However, the role of CTMP in pathological cardiac hypertrophy has not been identified. In this study, decreased expression of CTMP was observed in both human failing hearts
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