Milli-Q® CLX 8Series Water Purification System for Clinical Analyzers
Experience uninterrupted direct feed to your clinical analyzers with this next-generation water purification system that minimizes maintenance and maximizes lab productivity. With the support of MyMilli-Q™ digital capabilities, Milli-Q® CLX 8Series systems deliver high-quality purified water to analyzers with ease and peace of mind. As a result, you remain fully operational, enabling rapid patient results and supporting timely clinical decision-making.
Watch the video to learn about the Milli-Q® CLX 8Series water purification system.
Section Overview
- Consistent pure water quality
- Target 99.9% uptime with robust Milli-Q® system design and services
- Proven reliability in water purification
- Compact for easy integration
- Support more sustainable lab practices
- Facilitates data management, traceability and compliance
- Purified water specifications to analyzers
- Related Videos
- Ordering Information
Consistent pure water quality
To optimally support consistent calibrations and clinical testing, Milli-Q® CLX systems produce consistent-quality purified water that complies with feed water specifications for clinical analyzers. Purified water quality typically complies with CLSI GP 40 ED5-2024 guidelines for Clinical Laboratory Reagent Water (CLRW) and Special Reagent Water (SRW).
Reliability is achieved through a thoughtfully designed water purification chain that incorporates patented water purification technologies and multiple water quality sensors. For additional bacterial control, a sanitary sampling valve is available as an option.

A key component of the purification chain is the unique Elix® electrodeionization (EDI) module. Elix® EDI provides consistently high-quality pure water with the benefits of:
- No additional consumables compared to standard EDI, which requires additional consumables such as degasser and conditioning cartridges
- No resistivity drops compared to a standard deionization (DI), which requires frequent and costly cartridge replacements.
The Elix® EDI module requires only a small electric field that continuously regenerates the ion-exchange resins.
Target 99.9% uptime with robust Milli-Q® system design and services
Already able to achieve 99.6% uptime* with the Milli-Q® CLX 7000 systems, the Milli-Q® CLX 8Series with MyMilli-Q™ advanced digital capabilities lets your lab target 99.9% uptime thanks to a robust system design and enhanced service offering.
Highlights of this system that will maximize clinical lab uptime and productivity include:
- Full online access to system and water quality data eases traceability for audits†
- Predictive analytics with a Service Total Predict™ Plan lets us remotely monitor the health of key components and anticipate corrective actions
- 24/7 real-time monitoring of alerts and alarms to solve issues faster
- Remote troubleshooting for fast, professional diagnostics and potentially online repairs†
- No constraints or system shutdown when replacing consumables
- Optimally-sized, embedded tank so water is always available to complete tests
- Emergency bypass mode ensures continuous analyzer feed even if system is not operational; a new resistivity indicator (optional) ensures water quality control and timely replacement of the Q-Gard® polishing cartridge
- Simplified management of system, contract and consumables with online services and lifetime indicators
Each Milli-Q® service plan is highly customizable. Review service options here.
* Uptime obtained across all Milli-Q® CLX 7000 systems worldwide connected to MyMilli-Q™ Remote Care. Data available upon request.
† With connection to MyMilli-Q™ Remote Care.
Proven reliability in water purification
As an expert in laboratory water purification for more than 50 years with Milli-Q® systems, and decades of experience in clinical labs, this new solution offers the best reliability through:
- Robust manufacturing supply chain—from raw materials to system quality certification
- Durable core components (including hydraulic and electronic) validated to last at least 7 years.
- Certified service team delivers seamless lab integration, analyzer connection, and lifetime maintenance
Backed by our ISO 9001-certified quality management system, you’ll benefit from dependable performance and peace of mind in your clinical laboratory operations.
Compact for easy integration
The CLX system is equipped with the latest-generation touchscreen that is large, responsive and easy to navigate.
- All needed information is visible at-a-glance
- Can be viewed and controlled online via MyMilli-Q™ Remote Care
- On-screen instructions, convenient front access and RFID technology make it easy to monitor and replace consumable

Free up lab space with a compact (≤0.5 m2 footprint) water system. The vertical system design combines production, storage and distribution to analyzers, with an optional manual purified water dispenser.
Supports more sustainable lab practices
Reducing the environmental impact of water purification goes hand-in-hand with enhancing operational efficiency and cost-effectiveness – it’s better for the planet and better for your workflows.
Key innovations that support greater sustainability include:
- Mercury-free ech2o® UV solutions replace traditional mercury lamps and comply with upcoming regulations (RoHS Directive 2027):
- Bactericidal UV LEDs last twice as long, use less energy, and are more efficient, ensuring complete system and tank sanitization
- Excimer UV lamp for TOC monitoring (optional)
- Optimized lifetime of UV LEDs and pumps by monitoring specific use
- Water saving E.R.A.® technology acts on the RO recovery loop by recycling part of the water rejected to the drain. It reduces water waste by up to 50% while extending RO module and Progard® pack lifetimes
- Waste-reducing Elix® EDI technology eliminates the need for DI resin cylinder replacement and any other consumables
- Greener packaging:
- Product box made with sustainable forestry-certified cardboard, which is over 50% recycled content
- Protective foam inserts composed of over 80% recycled content
Facilitates data management, traceability and compliance
To facilitate compliance with regulatory requirements and accreditation processes, Milli-Q® CLX 8Series systems provide:
- Enhanced cybersecurity:
- Compliant with regulations (RED 2025 and CRA 2027)
- Software updates as needed to prevent cyberattacks.
- Full data traceability: Automatic recording of water quality, system performance, cartridge replacements, maintenance and service events support ISO 15189 and CLIA requirements for audits and accreditation.
- Mercury-free UV solutions: In anticipation of upcoming regulations (RoHS Directive 2027), ech2o® LEDs for bactericidal treatment and ech2o® excimer lamp for photo-oxidation in the TOC monitor replace mercury UV lamps.
- Purified water quality complies with CLSI GP 40 ED5-2024 guidelines for Clinical Laboratory Reagent Water (CLRW) and Special Reagent Water (SRW).
- Clinical analyzer specifications: Water quality fits with all the major clinical analyzer brand specifications (Abbott, Beckman Coulter, Roche Diagnostics, Siemens Healthineers, Sysmex and others) for patient diagnostics and clinical trials in immunology, clinical chemistry, hematology, hemostasis, etc.

A user-friendly interface shows all relevant system and water quality information at a glance. (A) displays the Tank water level; (B) displays water quality measurements; (C) shows the Cartridge status and time remaining before cartridges must be replaced
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