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Merck
CN

1708707

USP

丙戊酸

United States Pharmacopeia (USP) Reference Standard

别名:

2-丙基戊酸, 丙戊酸

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关于此项目

线性分子式:
(CH3CH2CH2)2CHCO2H
化学文摘社编号:
分子量:
144.21
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
202-777-3
MDL number:
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grade

pharmaceutical primary standard

API family

valproic acid

manufacturer/tradename

USP

refractive index

n20/D 1.425 (lit.)

bp

220 °C (lit.)

density

0.9 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCC(C(O)=O)CCC

InChI

1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)

InChI key

NIJJYAXOARWZEE-UHFFFAOYSA-N

Gene Information

human ... ALDH5A1(7915)

General description

本产品按照现行药典要求提供和指定。所有为支持本产品而提供的信息,包括 SDS 和任何产品信息小册子,均由药典颁发机构制定和发布。如需进一步的信息和支持,请访问现行药典网站。如需进一步信息和支持,请访问现行药典网站。

Application

丙戊酸USP参考标准品的预期用途是USP规定的指定质量测试和检测。也用于USP各论,例如:
  • 丙戊酸钠
  • 丙戊酸钠缓释胶囊
  • 丙戊酸钠迟释片
  • 丙戊酸钠缓释片
  • 丙戊酸钠注射液
  • 丙戊酸
  • 丙戊酸胶囊

Biochem/physiol Actions

抗惊厥药,同时还具有双相障碍症情绪稳定剂的功效

Analysis Note

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药,不可用于诊断、治疗或治愈任何疾病。

Other Notes

可能适用相应的销售限制。


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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

231.8 °F - closed cup

flash_point_c

111 °C - closed cup



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Brian L Le et al.
Research square (2021-04-07)
The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire or
Chi-Tso Chiu et al.
Pharmacological reviews, 65(1), 105-142 (2013-01-10)
The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar disorder (BD), a severe mental illness arising from complex interactions between genes and environment that drive deficits in cellular plasticity and resiliency. The therapeutic potential of
Radu M Nanau et al.
Clinical biochemistry, 46(15), 1323-1338 (2013-06-25)
Valproic acid is a widely-used first-generation antiepileptic drug, prescribed predominantly in epilepsy and psychiatric disorders. VPA has good efficacy and pharmacoeconomic profiles, as well as a relatively favorable safety profile. However, adverse drug reactions have been reported in relation with



全球贸易项目编号

货号GTIN
1708707-500MG04061838750532