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Merck
CN

1623626

USP

三氯蔗糖

United States Pharmacopeia (USP) Reference Standard

别名:

1,6-二氯-1,6-二脱氧 - β-D呋喃果糖基-4-氯-4-脱氧 - α-D-吡喃半乳糖苷, E955, 三氯蔗糖

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About This Item

经验公式(希尔记法):
C12H19Cl3O8
CAS号:
分子量:
397.63
Beilstein:
3654410
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

sucralose

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Sucralose USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生化/生理作用

一种人类可以检测到的合成甜味剂。可激活肠内分泌细胞上的 T1R2/T1R3 甜味受体,引起胰高血糖素样肽-1 和葡萄糖依赖性胰岛素肽的激素分泌增加。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sucralose--an overview of the toxicity data.
H C Grice et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38 Suppl 2, S1-S6 (2000-07-07)
Knut Erik Tollefsen et al.
The Science of the total environment, 438, 510-516 (2012-10-04)
Sucralose (1,6-dichloro-1,6-dideoxy-b-D-fructo-furanosyl 4-chloro-4-deoxy-a-D-galactopyranoside), sold under the trade name Splenda, has been detected in municipal effluents and surface waters in the United States and Europe. The environmental presence of sucralose has led to interest in the possibility of toxic effects in
Susan S Schiffman et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 16(7), 399-451 (2013-11-14)
Sucralose is a synthetic organochlorine sweetener (OC) that is a common ingredient in the world's food supply. Sucralose interacts with chemosensors in the alimentary tract that play a role in sweet taste sensation and hormone secretion. In rats, sucralose ingestion
V Lee Grotz et al.
Regulatory toxicology and pharmacology : RTP, 55(1), 1-5 (2009-05-26)
Sucralose is a non-nutritive sweetener used in a broad range of foods and beverages and is the non-nutritive sweetener in retail SPLENDA Sweetening Products, composed of sucralose and common food ingredients. A review of the extensive body of evidence that
I Knight
Canadian journal of physiology and pharmacology, 72(4), 435-439 (1994-04-01)
Sucralose is a new sweetener discovered during a collaborative research program between Tate & Lyle and Queen Elizabeth College of the University of London. It is made by selective substitution of sucrose hydroxyl groups by chlorine, resulting in a highly

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