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Merck
CN

1598405

USP

雷尼替丁 盐酸盐

United States Pharmacopeia (USP) Reference Standard

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经验公式(希尔记法):
C13H22N4O3S · HCl
CAS号:
分子量:
350.86
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard
secondary reference material (pharmaceutical)

API类

ranitidine

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

Cl[H].CN\C(NCCSCc1ccc(CN(C)C)o1)=C\[N+]([O-])=O

InChI

1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9-;

InChI key

GGWBHVILAJZWKJ-CHHCPSLASA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ranitidine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Ranitidine Injection
  • Ranitidine Tablets
  • Ranitidine in Sodium Chloride Injection
  • Ranitidine Oral Solution

生化/生理作用

H2 组胺受体拮抗剂;抗溃疡剂。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

相关产品

产品编号
说明
价格

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Travis Nemkov et al.
JCI insight, 6(3) (2020-12-23)
Computational models based on recent maps of the RBC proteome suggest that mature erythrocytes may harbor targets for common drugs. This prediction is relevant to RBC storage in the blood bank, in which the impact of small molecule drugs or
[The development of hemorrhagic vasculitis (Schönlein-Henoch disease) in a patient with a chronic stomach ulcer against a background of Sostril (ranitidine hydrochloride) therapy].
E N Glazunov et al.
Vestnik khirurgii imeni I. I. Grekova, 152(1-2), 102-103 (1994-01-01)
T S Gaginella et al.
Drug intelligence & clinical pharmacy, 17(12), 873-885 (1983-12-01)
Ranitidine is a selective, competitive histamine H2-receptor antagonist recently approved by the Food and Drug Administration for use in the short-term treatment of active duodenal ulcers and gastric hypersecretory conditions. Ranitidine is four to ten times more potent than cimetidine
Natalia Alonso et al.
The Biochemical journal, 459(1), 117-126 (2014-01-15)
7TMRs (seven-transmembrane receptors) exist as conformational collections in which different conformations would lead to differential downstream behaviours such as receptor phosphorylation, G-protein activation and receptor internalization. In this context, a ligand may cause differential activation of some, but not all
M B Evans et al.
Journal of pharmaceutical and biomedical analysis, 7(1), 1-22 (1989-01-01)
The selection, development, definition and validation of selective stability-indicating procedures for high-performance liquid chromatographic and thin-layer chromatographic analyses of ranitidine hydrochloride are described. The procedures used in conjunction can be applied to the quality assurance and stability assessments of both

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