1457902
USP
Nefazodone hydrochloride
United States Pharmacopeia (USP) Reference Standard
别名:
2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride, BMY-13754, MJ-13754-1, Serzone
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About This Item
经验公式（希尔记法）:
C25H32ClN5O2 · HCl
CAS号:
分子量:
506.47
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
pharmaceutical primary standard
API类
nefazodone
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.Cl
InChI
1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H
InChI key
DYCKFEBIOUQECE-UHFFFAOYSA-N
基因信息
human ... HTR2A(3356) , HTR2C(3358) , SLC6A2(6530) , SLC6A4(6532)
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应用
Nefazodone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Nefazodone Hydrochloride Tablets
生化/生理作用
Novel antidepressant; mixed 5-HT2A serotonin receptor antagonist/serotonin uptake inhibitor.
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Electrochemical characterisation of nefazodone hydrochloride and voltammetric determination of the drug in pharmaceuticals and human serum.
Uslu, Bengi, and Sibel A. Ozkan.
Analytica Chimica Acta, 462.1, 49-57 (2002)
Anne-Charlotte Dubbelman et al.
Journal of chromatography. A, 1374, 122-133 (2014-12-02)
The present study investigated the practical use of modern ultra-high performance liquid chromatography (UHPLC) separation techniques for drug metabolite profiling, aiming to develop a widely applicable, high-throughput, easy-to-use chromatographic method, with a high chromatographic resolution to accommodate simultaneous qualitative and
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