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Merck
CN

1368008

USP

3,3′,5-三碘代-L-甲状腺原氨酸

United States Pharmacopeia (USP) Reference Standard

别名:

O-(4-羟基-3-碘苯基)-3,5-二碘代-L-酪氨酸, T3, 碘噻罗宁

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About This Item

经验公式(希尔记法):
C15H12I3NO4
CAS号:
分子量:
650.97
Beilstein:
2710227
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

liothyronine

制造商/商品名称

USP

mp

234-238 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O

InChI

1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

InChI key

AUYYCJSJGJYCDS-LBPRGKRZSA-N

基因信息

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Liothyronine USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, standard stock, Liothyronine stock, and resolution solutions for assay, and identification test according to given below monographs of the United States Pharmacopeia (USP):
  • Thyroid
  • Levothyroxine Sodium Tablets
  • Liothyronine Sodium Tablets

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

STOT RE 1

靶器官

Thyroid,Cardio-vascular system,Kidney

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Liothyronine Sodium Tablets
United States Pharmacopeia, 34(4), 2640-2640 (2013)
Levothyroxine Sodium Tabletsl
United States Pharmacopeia, 42(2), 2618-2618 (2022)
Thyroid
United States Pharmacopeia, 40(5), 4362-4362 (2023)
Sara Santos Bernardes et al.
Cell and tissue research, 357(3), 803-814 (2014-05-21)
The role of reactive oxygen species (ROS) in muscle protein hydrolysis and protein oxidation in thyrotoxicosis has not been explored. This study indicates that ROS play a role in skeletal muscle wasting pathways in thyrotoxicosis. Two experimental groups (rats) were
Akihiro Mouri et al.
Psychoneuroendocrinology, 48, 147-161 (2014-07-13)
Attention deficit/hyperactivity disorder (ADHD) has been reported in association with resistance to thyroid hormone, a disease caused by a mutation in the thyroid hormone receptor β (TRβ) gene. TRβ is a key protein mediating down-regulation of thyrotropin (TSH) expression by

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