1337809
USP
亚胺培南 一水合物
United States Pharmacopeia (USP) Reference Standard
别名:
Primaxin 一水合物, Tienam 一水合物, （5R，6S）-6-[（（1R）-1-羟基乙基] -3-[[2-[（亚氨基甲基）氨基]乙基]硫代] -7-氧代-1-氮杂双环[3.2.0] hept-2 -烯-2-羧酸 一水合物
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所有图片(1)
About This Item
经验公式（希尔记法）:
C12H17N3O4S · H2O
CAS号:
分子量:
317.36
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
pharmaceutical primary standard
API类
imipenem
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
格式
neat
储存温度
−20°C
SMILES字符串
O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O
InChI
1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
InChI key
GSOSVVULSKVSLQ-JJVRHELESA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Imipenem monohydrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Imipenem
- Imipenem and Cilastatin for Injectable Suspension
- Imipenem and Cilastatin for Injection
生化/生理作用
亚胺培南一水合物是广谱 B -内酰胺抗生素。 它是碳青霉烯类“魔弹”抗生素的一种，用于严重感染。
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Bacteremia due to imipenem-resistant Roseomonas mucosa in a child with acute lymphoblastic leukemia.
Anne-Laure Michon et al.
Journal of pediatric hematology/oncology, 36(3), e165-e168 (2013-05-15)
Roseomonas are described as opportunistic pathogens rarely involved in human infections. Their identification requires molecular methods and their antimicrobial susceptibility pattern varies according to the species. We report the first case of bacteremia due to Roseomonas mucosa in a child
The deadly impact of extreme drug resistance in Acinetobacter baumannii.
Brad Spellberg et al.
Critical care medicine, 42(5), 1289-1291 (2014-04-17)
Imipenem heteroresistance: high prevalence among Enterobacteriaceae Klebsiella pneumoniae carbapenemase producers.
Carolina Silva Nodari et al.
Journal of medical microbiology, 64(Pt 1), 124-126 (2014-10-30)
Hao-Yuan Lee et al.
Critical care medicine, 42(5), 1081-1088 (2014-01-08)
Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. Retrospective study. All adult ICUs
Yi-Jiun Pan et al.
Antimicrobial agents and chemotherapy, 59(2), 1038-1047 (2014-12-03)
Klebsiella pneumoniae is an important human pathogen associated with a variety of diseases, and the prevalence of multidrug-resistant K. pneumoniae (MDRKP) is rapidly increasing. Here we determined the capsular types of 85 carbapenem-resistant K. pneumoniae (CRKP) strains by wzc sequencing
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