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经验公式(希尔记法):
C16H16ClNO2S · H2SO4
化学文摘社编号:
分子量:
419.90
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
9967887
产品名称
硫酸氯吡格雷, United States Pharmacopeia (USP) Reference Standard
InChI key
FDEODCTUSIWGLK-RSAXXLAASA-N
SMILES string
OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl
InChI
1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1
grade
pharmaceutical primary standard
API family
clopidogrel, clopidogrel
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... P2RY12(64805)
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Analysis Note
这些产品仅供测试和分析使用。它们不适用于人类或动物的给药,不可用于诊断、治疗或治愈任何疾病。
Application
硫酸氢氯吡格雷USP参考标准品的预期用途是美国药典规定的指定质量测试和检测。也用于下列USP专论:
- 硫酸氢氯吡格雷
- 氯吡格雷片
- 氯吡格雷复合口服混悬液(Clopidogrel Compounded Oral Suspension)
Disclaimer
可能适用相应的销售限制。
General description
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Clopidogrel Bisulfate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(1), 1109-1109 (2020)
Clopidogrel Compounded Oral Suspension
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(5), 1111-1111 (2014)
Kailas S Khomane et al.
Journal of pharmaceutical sciences, 101(7), 2408-2416 (2012-04-11)
Being a density violator, clopidogrel bisulfate (CLP) polymorphic system (forms I and II) allows us to study individually the impact of molecular packing (true density) and thermodynamic properties such as heat of fusion on the compaction behavior. These two polymorphs
Clopidogrel Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(1), 1111-1111 (2020)
Kyoung-Woo Seo et al.
Clinical therapeutics, 36(11), 1588-1594 (2014-09-15)
Platelet-function suppression with antiplatelet therapy is effective in preventing and treating cardiovascular disease. Clopidogrel is a thienopyridine derivative that blocks platelet activation by adenosine diphosphate receptor binding. This study demonstrates the effects of generic clopidogrel bisulfate in comparison to branded
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