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BP1234

来曲唑

British Pharmacopoeia (BP) Reference Standard

别名:

4,4′-(1H-1,2,4-三唑-1-基亚甲基）双苄腈

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About This Item

经验公式（希尔记法）:
C17H11N5
CAS号:
112809-51-5
分子量:
285.30
MDL编号:
MFCD00866241
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

质量水平

100

API类

letrozole

表单

powder

保质期

limited shelf life, expiry date on the label

制造商/商品名称

BP

应用

pharmaceutical
pharmaceutical small molecule

包装形式

neat

储存温度

2-8°C

SMILES字符串

N#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3

InChI

1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H

InChI key

HPJKCIUCZWXJDR-UHFFFAOYSA-N

基因信息

human ... CYP19A1(1588)

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Letrozole BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Letrozole Tablets

    • 生化/生理作用

    来曲唑是一种非甾体芳香酶抑制剂。
    来曲唑是第三代非甾体芳香酶抑制剂。 它是芳香酶系统的竞争性抑制剂，因此可抑制雄激素向雌激素转化。来曲唑通过竞争性结合到该酶的细胞色素P450亚基的血红素上而抑制芳香酶，导致所有组织中雌激素的生物合成减少。

    包装

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他说明

    Sales restrictions may apply.

    象形图

    Health hazard
    GHS08

    警示用语：

    Warning

    危险声明

    H361fd,H373

    危险分类

    Repr. 2 - STOT RE 2

    储存分类代码

    11 - Combustible Solids

    WGK

    WGK 3

    闪点(°F)

    Not applicable

    闪点(°C)

    Not applicable

    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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