568533-U
Discovery® HS C18 (5 µm) HPLC Columns
L × I.D. 25 cm × 10 mm, HPLC Column
别名:
Discovery RP18 HPLC Column
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关于此项目
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 10 mm
Particle size:
5 μm
Matrix active group:
C18 (RP18), C18 (octadecyl) phase
Pore size:
120 Å
Matrix:
silica gel, high purity, spherical particle platform, fully porous particle
产品名称
Discovery® HS C18 高效液相色谱柱, 5 μm particle size, L × I.D. 25 cm × 10 mm
material
stainless steel column
Quality Segment
agency
suitable for USP L1
product line
Discovery®
feature
endcapped
manufacturer/tradename
Discovery®
packaging
1 ea of
extent of labeling
20% Carbon loading
parameter
≤70 °C temp. range, 400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
25 cm × 10 mm
surface area
300 m2/g
surface coverage
3.2 μmol/m2
impurities
<10 ppm metals
matrix
silica gel, high purity, spherical particle platform, fully porous particle
matrix active group
C18 (RP18), C18 (octadecyl) phase
particle size
5 μm
pore size
120 Å
operating pH range
2-8
application(s)
food and beverages
separation technique
reversed phase
General description
Discovery® HS C18 HPLC column is specifically developed for pharmaceutical analyses and purification.
Application
- Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).
- A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).
- Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).
Features and Benefits
- 稳定性好、低流失，适用于 LC-MS 分析
- 提供有适用于分析型到制备型的各种规格
- 稳定性好，以确保柱与柱和批与批之间之间优良的重现性
- 更强的疏水性能够更好地分离难分析化合物
Legal Information
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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