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Merck
CN

51099AST

Supelco

Astec® Cellulose DMP Chiral (5 μm) HPLC Column

L × I.D. 25 cm × 4.6 mm, HPLC Column

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别名:
Cellulose DMP Chiral Stationary Phase
UNSPSC代码:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Astec ® 纤维素 DMP 手性 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

物料

stainless steel column

质量水平

Agency

suitable for USP L40

产品线

Astec®

包装

pkg of 1 ea

制造商/商品名称

Astec®

参数

0-40 °C temperature
50 bar pressure (725 psi)

技术

HPLC: suitable

长度 × 内径

25 cm × 4.6 mm

基质

fully porous particle
silica gel high purity, spherical
silica gel particle platform

基质活性基团

cellulose, DMPC- phase

粒径

5 μm

孔径

100 Å pore size

工作pH值

3.5-6.8

分离技术

chiral

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相关类别

一般描述

Astec®纤维素 DMP HPLC 色谱柱在正相、极性有机和 SFC 条件下分离多种手性化合物。它们具有高效率、高负载能力和极好的色谱柱使用寿命。Astec®纤维素DMP具有与其他DMPC衍生的纤维素CSP相当的性能,但价格却低得多,是每个手性色谱柱HPLC或SFC筛选方案的必备必备成分。Astec ® 纤维素 DMP 与其他 Astec ® CSP 互补,包括 CHIROBIOTIC ®、CYCLOBOND 和 P-CAP 产品线。

描述:球形多孔二氧化硅,涂有DMPC(氨基甲酸二甲基苯酯)衍生的纤维素
颗粒直径:5μm
使用范围: 正相、极性有机和 SFC 模式下的小分子对映异构体分离

应用


  • Enantioseparation of Synthetic Cathinones Enantiomers with Tertiary Amine Structure in Urine and Plasma.: This research investigates the application of the Astec Cellulose DMP Chiral HPLC Column for the enantioseparation of synthetic cathinones enantiomers in biological samples. The study demonstrates the column′s efficacy in separating enantiomers with high resolution and sensitivity, particularly in complex matrices such as urine and plasma. This highlights the column′s utility in forensic and clinical analysis, providing a robust method for the detection and quantification of chiral drugs in biological samples (Meetani et al., 2019).

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法律信息

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
CYCLOBOND is a trademark of Sigma-Aldrich Co. LLC
P-CAP is a trademark of Sigma-Aldrich Co. LLC

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Katrijn De Klerck et al.
Journal of pharmaceutical and biomedical analysis, 69, 77-92 (2012-03-01)
Chirality has a significant impact on drug discovery and development processes in the pharmaceutical industry. As the number of enantiopure drugs launched onto the market is yearly increasing, the need for fast and performant enantioseparation methods with minimal costs is
Katrijn De Klerck et al.
Journal of chromatography. A, 1328, 85-97 (2014-01-21)
Since their introduction on the market the applicability of immobilized polysaccharide-based chiral stationary phases in high-performance liquid chromatography has been thoroughly investigated. These immobilized phases have the benefit to be applicable with a wide range of modifiers, potentially extending the

相关内容

Separate a wide range of chiral compounds via normal phase, polar organic, and SFC conditions; useful in pharma, chemical, & environmental industry applications.

Chromatograms

application for SFCapplication for HPLCapplication for HPLCapplication for HPLC展开

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