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主要文件

安全信息

T9326

Sigma-Aldrich

凝血酶 人

BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE)

别名:

IIa 因子

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25 MG
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25 MG
¥1,974.51

About This Item

MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54

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重组

expressed in HEK 293 cells

质量水平

产品线

BioUltra

方案

≥95% (SDS-PAGE)

表单

aqueous solution

比活

≥2,000 units/mg protein

分子量

37.4 kDa

UniProt登记号

运输

dry ice

储存温度

−70°C

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此商品
S7576PHR1591A7986
Shikonin ≥98% (HPLC)

S7576

Shikonin

Atovaquone Pharmaceutical Secondary Standard; Certified Reference Material

PHR1591

Atovaquone

Atovaquone ≥98% (HPLC)

A7986

Atovaquone

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

form

powder

form

powder or solid

form

-

form

powder

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: soluble, chloroform: soluble

solubility

methanol: 1 mg/mL

solubility

-

solubility

DMSO: >10 mg/mL

一般描述

凝血酶是止血方面的最终凝血蛋白酶,促进促凝血和抗凝血作用。

应用

凝血酶被用于重组融合蛋白的位点特异性切割,这些重组融合蛋白具有可接近的凝血酶识别位点以除去亲和标签。凝血酶已用在一项评估法国冻干血浆的体外止血特性的研究中。 [1]

单位定义

活性以NIH单位表示,它是通过与NIH凝血酶参考标准品直接对比而获得的。

外形

以 20mM MES,pH 6.0,500mM 氯化胆碱的溶液形式提供

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
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    分析证书(COA)

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    Katerina Zakharova et al.
    International journal of molecular sciences, 22(14) (2021-07-25)
    Redβ is a 261 amino acid protein from bacteriophage λ that promotes a single-strand annealing (SSA) reaction for repair of double-stranded DNA (dsDNA) breaks. While there is currently no high-resolution structure available for Redβ, models of its DNA binding domain
    Ute Metzger et al.
    Proceedings of the National Academy of Sciences of the United States of America, 106(34), 14309-14314 (2009-08-27)
    Ergot alkaloids are toxins and important pharmaceuticals that are produced biotechnologically on an industrial scale. The first committed step of ergot alkaloid biosynthesis is catalyzed by dimethylallyl tryptophan synthase (DMATS; EC 2.5.1.34). Orthologs of DMATS are found in many fungal
    Christophe Martinaud et al.
    Anesthesiology, 117(2), 339-346 (2012-06-29)
    French lyophilized plasma (FLyP) is used routinely by the French Armed Forces in war settings. The authors compared concentrations of coagulation proteins and global in vitro hemostatic properties in FLyP and in the same plasma before lyophilization to assess the
    Dmitriy Krepkiy et al.
    Nature, 462(7272), 473-479 (2009-11-27)
    Despite the growing number of atomic-resolution membrane protein structures, direct structural information about proteins in their native membrane environment is scarce. This problem is particularly relevant in the case of the highly charged S1-S4 voltage-sensing domains responsible for nerve impulses
    Diane Moujalled et al.
    Cell death & disease, 12(1), 133-133 (2021-01-30)
    Necroptosis is a pro-inflammatory cell death program executed by the terminal effector, mixed lineage kinase domain-like (MLKL). Previous studies suggested a role for the necroptotic machinery in platelets, where loss of MLKL or its upstream regulator, RIPK3 kinase, impacted thrombosis

    商品

    Thrombin Factor IIa is an endolytic serine protease that selectively cleaves the Arg--Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.

    凝血酶因子IIa是一种内切丝氨酸蛋白酶,可选择性地裂解纤维蛋白原的Arg -Gly键,形成纤维蛋白并释放纤维蛋白肽A和B。

    Proteases for biotinylated tag removal for protein purification workflows with related reagents and technical resources.

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